ALYREF ENHANCES BREAST CANCER PROGRESSION BY REGULATING EZH2

ALYREF enhances breast cancer progression by regulating EZH2

Breast cancer is one of the most Stockings common malignant tumors in women worldwide.Similarly, Canine mammary tumors (CMTs) are mostly diagnosed as spontaneous diseases in female dogs.Many studies have suggested that CMTs serve as good models for human breast cancer.However, comparative approaches to histone modifications are still lacking.This s

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Assessment of Osteoporosis and Vitamin D3 Deficiency in Patients with Idiopathic Benign Paroxysmal Positional Vertigo (BPPV)

Background and objectives: Osteoporosis and vitamin D3 deficiency may be risk factors Serum Spray of benign paroxysmal positional vertigo (BPPV).The aim of this study was to assess the prevalence of osteoporosis and 25(OH) vitamin D3 deficiency in a group of patients with idiopathic benign paroxysmal positional vertigo.Materials and Methods: Thirty

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Molecular analysis of the full-length VP2 gene of Brazilian strains of canine parvovirus 2 shows genetic and structural variability between wild and vaccine strains

Canine parvovirus 2 (CPV-2), a highly contagious virus, affects dogs worldwide.Infected animals present severe and acute gastroenteritis which may culminate in death.CPV-2 VP2 protein is responsible for important biological functions related to virus-host interactions.Herein we obtained VP2 full-length gene sequences from Brazilian dogs with bloody

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Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans

The generation of high-affinity antibodies depends on somatic hypermutation (SHM).SHM is initiated by the activation-induced cytidine deaminase (AID), which generates uracil (U) lesions in the B-cell receptor (BCR) encoding genes.Error-prone processing of U lesions creates a typical spectrum of point mutations during SHM.The aim of this study was t

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Feasibility study on a stabilization method based on full spectrum reallocation for spectra having non-identical momentum features

Methodology for suppressing or recovering the distorted spectra, which may occur due to mutual non-uniformity and nonlinear response when a multi-detector is simultaneously operated for gamma spectroscopy, is presented with respect to its applicability to stabilization of spectra having the non-identical feature using modified full spectrum realloc

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